Drug side effects and the elderly
Researchers in Britain have found that commonly used
drugs prescribed to half of those that are 65 or older lead to an increased
incidence of death and mental health decline, especially when the drugs are
prescribed in combination. The researchers' findings, which was published in
the August 2011 Journal of the American Geriatrics Society, suggest that these
types of drugs negatively affect the brain and increase the risk of decline and
death. The study found that patients taking a combination of prescription drugs
were at greater risk.
Elderly people take approximately three times the amount
of medications that younger people do. Although the elderly are prescribed a
wide array of drugs, the most common drugs are heart medications, statins,
benzodiazepines, and antidepressants.
Drugs that treat the cardiovascular system can result in
nausea, vomiting, weight loss, anorexia, and bleeding problems. Statins' side
effects include muscle weakness and pain (the most serious that can be life
threatening), headaches, nausea, vomiting, constipation, diarrhea, skin rash,
and general weakness.
Benzodiazepines can result in sedation, confusion, and
falls. The side effects of antidepressants include sedation, confusion, falls,
low blood pressure, and urinary retention. Antidepressants also thin the blood.
They decrease blood clotting capacity, increasing the risk for stomach and
uterine bleeding. Add over the counter NSAID's taken at the same time and the
risk doubles.
Other common drugs' side effects
Other commonly prescribed drugs also have a host of
potentially harmful side effects. Examples include:
* Antipsychotic medications that are used to treat
"mental disorders" can result in confusion, sedation, low blood
pressure, falls, urinary retention, Parkinsonism (involuntary shaking and
twitching), and tardive dyskinesia (repetitive body movements)
* Antihistamines used to treat allergies can result in
confusion, sedation, low blood pressure, falls, sleep disturbance, and urinary
retention
* Drugs that relieve nausea can lead to confusion,
sedation, low blood pressure, falls, urinary retention, Parkinsonism, and
tardive dyskinesia
* Pain medication can result in constipation, confusion,
& sedation. Even over the counter medications can result in serious liver
and gastrointestinal side effects.
* Drugs to treat Parkinson's disease can result in
confusion, dizziness, low blood pressure, and an increase in cardiovascular
toxicity
* Drugs to relieve muscle spasms can result in dry mouth,
constipation, urinary retention, and delirium
* Urinary incontinence drugs can result in dry mouth,
constipation, urinary retention, delirium, and confusion
All of these side effects relate to individual drugs. Imagine how these side effects can be compounded by taking several prescription drugs at a time.