Thursday, December 27, 2012


Drug side effects and the elderly

Researchers in Britain have found that commonly used drugs prescribed to half of those that are 65 or older lead to an increased incidence of death and mental health decline, especially when the drugs are prescribed in combination. The researchers' findings, which was published in the August 2011 Journal of the American Geriatrics Society, suggest that these types of drugs negatively affect the brain and increase the risk of decline and death. The study found that patients taking a combination of prescription drugs were at greater risk.
Elderly people take approximately three times the amount of medications that younger people do. Although the elderly are prescribed a wide array of drugs, the most common drugs are heart medications, statins, benzodiazepines, and antidepressants.

Drugs that treat the cardiovascular system can result in nausea, vomiting, weight loss, anorexia, and bleeding problems. Statins' side effects include muscle weakness and pain (the most serious that can be life threatening), headaches, nausea, vomiting, constipation, diarrhea, skin rash, and general weakness.

Benzodiazepines can result in sedation, confusion, and falls. The side effects of antidepressants include sedation, confusion, falls, low blood pressure, and urinary retention. Antidepressants also thin the blood. They decrease blood clotting capacity, increasing the risk for stomach and uterine bleeding. Add over the counter NSAID's taken at the same time and the risk doubles.

Other common drugs' side effects

Other commonly prescribed drugs also have a host of potentially harmful side effects. Examples include:

* Antipsychotic medications that are used to treat "mental disorders" can result in confusion, sedation, low blood pressure, falls, urinary retention, Parkinsonism (involuntary shaking and twitching), and tardive dyskinesia (repetitive body movements)

* Antihistamines used to treat allergies can result in confusion, sedation, low blood pressure, falls, sleep disturbance, and urinary retention

* Drugs that relieve nausea can lead to confusion, sedation, low blood pressure, falls, urinary retention, Parkinsonism, and tardive dyskinesia

* Pain medication can result in constipation, confusion, & sedation. Even over the counter medications can result in serious liver and gastrointestinal side effects.

* Drugs to treat Parkinson's disease can result in confusion, dizziness, low blood pressure, and an increase in cardiovascular toxicity

* Drugs to relieve muscle spasms can result in dry mouth, constipation, urinary retention, and delirium

* Urinary incontinence drugs can result in dry mouth, constipation, urinary retention, delirium, and confusion

All of these side effects relate to individual drugs. Imagine how these side effects can be compounded by taking several prescription drugs at a time.

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